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Both medications, with the support of lifestyle changes, can significantly enhance weight loss results

In addition to HbA1c levels, fasting plasma glucose, fasting insulin, plasma glucagon, proinsulin, proinsulin-to-insulin ratio, and HOMA-insulin resistance were all significantly reduced after 56 weeks of treatment with semaglutide [4]

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Some people use these medications just during the first few days at new dose levels to make the adjustment period more tolerable

Begin exploring long-term dietary sustainability